// Definition
Specialized cells located at the base of the trichome gland head, at the abscission layer where the head meets the stalk. These cells contain many of the synthase enzymes responsible for cannabinoid and terpene biosynthesis.
// From the Episode
Dr. Mark referenced Paul Malberg's pioneering work (funded by David Watson) showing that stipe cells at the base of the trichome head are where cannabinoid synthases exist. He explained that the biosynthetic pathway of cannabinoids intersects with the terpene pathway at this location, describing cannabinoids as 'phenylated terpenoids.' Chimera confirmed the stipe cells are at the abscission layer at the bottom of the gland, noting that if the head breaks cleanly it will be open, but if it breaks with the top of the stalk plugging the hole, it would be sealed.