// Science · Glossary

Clinical Endocannabinoid Deficiency

⚗️ Science First mentioned: Ep. 080

The theory that some chronic conditions (migraines, fibromyalgia, IBS) result from deficient endocannabinoid tone, and that supplementing with phytocannabinoids can restore balance to a depleted endocannabinoid system.

Discussed in depth in ep080. The panel talked about receptors in our bodies designed for cannabinoids, the concept of endocannabinoid deficiency, and homeostasis. They compared the endocannabinoid receptor system to the opioid receptor system, noting how supplementing cannabinoids could restore balance. Related to magnesium deficiency as another nutrient depletion parallel.

Ep. 080 Hash Church LXXX 80