// Definition
The practice of tailoring cannabis dosage amount, cannabinoid ratios, and delivery methods (oral, transdermal, suppository, inhalation) to specific medical conditions. Different ailments may require different cannabinoid profiles, doses, and routes of administration for optimal therapeutic effect.
// From the Episode
A nearly 30-minute discussion in Episode 054. The panel explored how different delivery methods suit different conditions: transdermal patches for localized pain (with one panelist noting the pain 'would come back because the transdermals' wore off), suppositories for systemic absorption avoiding first-pass metabolism, and oral dosing for sustained release. Mark Scialdone discussed how patients sometimes 'start to avoid their dose, skip their doses' when the regimen isn't properly calibrated. The discussion emphasized starting at very small doses and titrating up.
// Source
Ep. 054 Hash Church LIII 53 →