// Science · Glossary

Thiols and Thiolates in Cannabis

⚗️ Science First mentioned: Ep. 245

Sulfur-containing volatile compounds responsible for the pungent, skunky, garlicky, and oniony aromas in cannabis. N-butanethiol-1 (found in actual skunk spray) is one key thiol. These compounds were historically bred out during prohibition because their extreme odor attracted law enforcement attention.

Abstract Labs discovered long-chain sulfur compounds in cannabis. Bubbleman previously called these 'alcohol-soluble terpenes' because they survived water hash washing while other aromatics washed away. GMO cultivar acts as an 'amplifier' for thiol expression in breeding. Post-legalization, breeders can now safely select for these loud profiles. Brian observed that some cultivars with subdued flower aroma produce amplified hash aroma.

Ep. 245 CHA Regenerative Roots and Living Soil