// Science · Glossary

THCA Membrane Penetration

⚗️ Science First mentioned: Ep. 123

Research finding that THCA (non-decarboxylated THC) can penetrate biological membranes in certain conditions but 'naked' THCA cannot due to molecular size and polarity. This has implications for oral and sublingual delivery of raw cannabis preparations.

Discussed in ep 123 in context of dry sift consumption and THCA therapeutics. The distinction between decarboxylated and raw cannabinoid delivery is important for medical patients who want therapeutic benefits without psychoactive effects.

Ep. 123 Hash Church CXX 120