// Science · Glossary

Terpinolene Anxiety Connection

⚗️ Science First mentioned: Ep. 186

The association between terpinolene-rich narrowleaf drug cultivars and anxiety induction in some users. Bubbleman described personal experience where terpinolene-dominant strains caused his first anxiety and panic attacks, exacerbating pain rather than relieving it.

Narrowleaf drug cultivars (sativa-type) tend to be terpinolene-rich. Bubbleman noted he never experienced anxiety until encountering these cultivars, contrasting with his positive experience using lower-THC hash that was super mellow. Highlights the importance of chemotype awareness in strain selection for medical patients. Karma Genetics referenced as producing terpinolene-dominant varieties.

Ep. 186 HC 5.0 Ep 6