// Science · Glossary

Nanoemulsification

⚗️ Science First mentioned: Ep. 212

A process that creates ultra-small (sub-200 nanometer) droplets of cannabis oil suspended in water using high-shear mixing or microfluidizers, dramatically increasing bioavailability and enabling rapid onset of effects in beverages and edibles. Similar to how milk is naturally emulsified fat in water.

Dr. Mark Scialdone explained nanoemulsification using milk as an analogy and described how a 5mg nanoemulsified gummy produces noticeable effects even in daily THC users, compared to traditional edibles requiring higher doses. He noted that microfluidizers (sending '12 lanes of traffic through a 2-lane tunnel') produce superior results to sonicators, which can pit their tips. Aten described making a 1000mg nanoemulsified drink for 11 years using sonication.

Ep. 212 Pre-Spannabis: Nanoemulsions, Cold Rooms, and Skunkman Sam Legacy