// Science · Glossary

Gas Chromatography (GC)

⚗️ Science First mentioned: Ep. 226

An analytical chemistry technique used to separate and identify volatile compounds in cannabis. GC is particularly suited for analyzing decarboxylated products like hemp-derived Delta-8 and Delta-9 THC distillates, where acidic precursor forms are absent.

Dr. Mark explained on episode 226 that Cayman Chemical developed and published an application note on using gas chromatography instead of HPLC to analyze Delta-8 products, inspired by KCA lab's Dr. Richard Markx. Since hemp-derived cannabinoid products have already been decarboxylated, there are no acid forms to worry about, making GC a valid and often superior analytical approach for detecting isomer contaminants.

Ep. 226 Father's Day, Wade Laughter Tribute & Terpene Profiles