// Science · Glossary

Endocannabinoid Receptor Lock and Key

⚗️ Science First mentioned: Ep. 088

The lock-and-key model of how cannabinoids interact with the endocannabinoid system, where CB1 and CB2 receptors are the 'locks' and molecules like THC and CBD are the 'keys' that open them to produce therapeutic effects.

The panel discussed the endocannabinoid system in depth, explaining how receptors work as a regulatory mechanism in the body. The discussion covered how THC and CBD act differently on different receptors, and how this understanding is fundamental to understanding why cannabis medicine works. The conversation also touched on how this system exists for our receptors and that cannabis molecules unlock these naturally occurring pathways.

Ep. 088 Hash Church 87 LXXXVII