// Science · Glossary

Conazole Fungicides

⚗️ Science First mentioned: Ep. 069

A class of systemic fungicides including myclobutanil (Eagle 20), propiconazole, and tebuconazole used on cannabis. They have low toxicity at room temperature but undergo thermal decomposition when heated during smoking or dabbing, releasing dangerous byproducts including hydrogen cyanide.

Mark Scialdone gave a detailed chemistry breakdown explaining that myclobutanil contains a benzylic cyanide group that undergoes thermal elimination when heated. The resulting decomposition products are far more dangerous than the fungicide itself. This is why systemic pesticides are particularly dangerous in cannabis that will be smoked. Even steam distillation may not remove these compounds due to similar boiling points to terpenes.

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