// Medicine · Glossary

Cannabis Edible Microdosing

🩺 Medicine First mentioned: Ep. 261

The practice of consuming very low doses of 1-5mg THC in cannabis edibles for controlled, predictable effects, recognizing that edible tolerance is independent of smoking tolerance and that liver metabolism varies enormously between individuals.

Vanessa (Italian-American cannabis chef) pioneered approach. Started at Berkeley during Prop 215 era with 100g Blue Dream bubble hash from Humboldt. Early mistake: 8 grams into 12 cookies at approximately 266mg each. Book How to Eat Weed and Have a Good Time focuses on low-dose entertaining. Bubbleman maxes out at 30mg edibles despite heavy daily dabbing. Key insight: edible tolerance does not equal smoking tolerance. Some people metabolize extremely fast due to genetics. Vanessa emphasizes never giving medical advice since everyone's metabolism is different.

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