// Definition
Beta-caryophyllene is a sesquiterpene highly prevalent in most cannabis strains that acts as a CB2 receptor agonist, meaning it binds to and activates the CB2 receptor similarly to CBD. This contributes to the entourage effect by upregulating cannabinoid receptor expression through increasing cell membrane fluidity.
// From the Episode
Mark Scialdone provided detailed chemistry, explaining that beta-caryophyllene fits into the CB2 receptor and turns it on (agonist), increasing the fluidity of the cell membrane which opens the cell for business and upregulates cannabinoid receptor expression.
// Source
Ep. 062 Hash Church LXII 62 →